Clinical Trials for Thyroid Tumors
COX-2 and VEGF expression in canine thyroid tumors

Eligibility Requirements
• Dogs with thyroid tumors who have had their tumors surgically biopsied

Study Objective
This study examines whether COX-2 and VEGF expression in thyroid tumors can predict outcome of disease.

Compensation
This study is not funded. Please click on link for more details. .

Location of Trial
North Grafton, MA

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Phase Ib study of GS-424044 in dogs with malignant neoplasia

Eligibility Requirements
• Dogs with advanced solid tumors (mainly carcinomas and sarcomas)
• Dogs with tumor type confirmed by histology (for solid tumors)
• Dogs must weigh at least 10.0kg
• Dogs must be otherwise healthy and at least one year of age.
• Have adequate organ function as specified by standard laboratory tests

Study Objective
The purpose of this study is to investigate a new chemotherapy drug as treatment for dos with malignant tumors.

Compensation
This study is partially funded. Please click on link for more details.

Location of Trial
Athens, GA

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Liposomal clodronate in canine cancer (excluding mast cell tumor, hemangiosarcoma and malignant histiocytosis)

Eligibility Requirements
• Dogs with biopsy-confirmed cancers (excluding mast cell tumor, hemangiosarcom and malignant histiocytosis) are potentially eligible
• The tumor must be less than 8cm (approximately 3.5 inches) in diameter and located in an easily accessible area for biopsy.
• Dogs must have good function of liver and kidneys and acceptable blood cell counts.
• Dogs must be free of underlying disease.
• OWNERS MUST CONSENT TO A POSTMORTEM EXAM (AUTOPSY) AT THE TIME THEIR PET DIES OR IS EUTHANIZED.

Study Objective
The goals of this study are to demonstrate liposomal clodronate as a safe and effective cancer therapy and to determine the anti-tumor activity of liposomal clodronate against a variety of canine tumors.

Compensation
This study is partially funded. Please click on link for more details.

Location of Trial
Fort Collins, CO

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Satraplatin for any tumor, including lymphoma

Eligibility Requirements
• Any tumor, including lymphoma confirmed by histopathology or cytology

Study Objective
To determine efficacy of using Satraplatin for various types of cancer using 5mg/m2 daily (orally).

Compensation
This study is partially funded. Please click on link for more details.

Location of Trial
Columbia, MO

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“Smokey taught me the value of leaving no stone unturned in the search for better therapies and
the importance of hope.”
               - Dr Gerald Post